Review: in people with bipolar disorder, short term antidepressants improve clinical response, although tricyclics risk inducing mania.
نویسندگان
چکیده
Gijsman HJ, Geddes JR, Rendell JM, et al. Antidepressants for bipolar depression: A systematic review of randomized, controlled trials. Am J Psychiatry 2004;161:1537–47. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
منابع مشابه
Antidepressants for bipolar disorder: A meta-analysis of randomized, double-blind, controlled trials
OBJECTIVE To examine the efficacy and safety of short-term and long-term use of antidepressants in the treatment of bipolar disorder. DATA SOURCES A literature search of randomized, double-blind, controlled trials published until December 2012 was performed using the PubMed, ISI Web of Science, Medline and Cochrane Central Register of Controlled Trials databases. The keywords "bipolar disorde...
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Although antidepressants may increase the risk of switching to mania in bipolar disorder (BD), clinicians have been using antidepressants to treat patients with bipolar depression. Appropriate treatments for bipolar depression remain controversial. In BD, antidepressants comprise a double-edged sword in terms of their efficacy in treating depression and the increased risk of switching. This rev...
متن کامل[Manic episodes during antidepressant treatment in bipolar disorder].
OBJECTIVES To review the literature on antidepressant-induced mania, its incidence, clinical presentation, risk factors and treatment. METHODS A Medline search of studies published between 1970 and 2001 was carried out. Open and controlled studies as well as case series with data from more than five patients were included. RESULTS Antidepressant induced mania may differ clinically from spon...
متن کاملThe neurobiology of the switch process in bipolar disorder: a review.
OBJECTIVE The singular phenomenon of switching from depression to its opposite state of mania or hypomania, and vice versa, distinguishes bipolar disorder from all other psychiatric disorders. Despite the fact that it is a core aspect of the clinical presentation of bipolar disorder, the neurobiology of the switch process is still poorly understood. In this review, we summarize the clinical evi...
متن کاملBipolar disorder.
INTRODUCTION Bipolar disorder, with mood swings between depression and mania, may affect up to 1.5% of adults, and increases the risk of suicide and disability. Most people improve over time, but two thirds may have residual dysfunction, and at least 40% may have recurrent episodes. METHODS AND OUTCOMES We conducted a systematic review and aimed to answer the following clinical questions: Wha...
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ورودعنوان ژورنال:
- Evidence-based mental health
دوره 8 2 شماره
صفحات -
تاریخ انتشار 2005